3-羟基-4-甲氧基苯甲酸甲酯合成路线

199327-61-27-甲氧基-6-(3-吗啉-4-基丙氧基)喹唑啉-4(3H)-酮

参考文献

Seimbille, Yann; Phelps, Michael E.; Czernin, Johannes; Silverman, Daniel H. S.
Journal of Labelled Compounds and Radiopharmaceuticals, 2005 , vol. 48, # 11 p. 829 - 843

6702-50-73-羟基-4-甲氧基苯甲酸甲酯+

100-39-0溴化苄

164161-49-35-苄氧基-4-甲氧基-2-硝基苯甲酸甲酯

参考文献

KIRIN BEER KABUSHIKI KAISHA
Patent: EP1153920 A1, 2001 ;

6702-50-73-羟基-4-甲氧基苯甲酸甲酯

117258-25-0

参考文献

Huber, Edward W.; Kane, John M.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 7 p. 1957 - 1961

6702-50-73-羟基-4-甲氧基苯甲酸甲酯

90564-40-23-羟基-4-甲氧基-2-硝基苯甲酸甲酯

参考文献

KALYPSYS, INC.; Govek, Steven P.; Shiau, Andrew K.; Noble, Stewart A.; Thomas, David J.
Patent: US2013/116279 A1, 2013 ;
Location in patent: Paragraph 0279 ;

6702-50-73-羟基-4-甲氧基苯甲酸甲酯

912556-91-3吉非替尼中间体B

参考文献

Li, Ri-Dong; Zhang, Xin; Li, Qiao-Yan; Ge, Ze-Mei; Li, Run-Tao
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 12 p. 3637 - 3640

6702-50-73-羟基-4-甲氧基苯甲酸甲酯

692059-41-94-氯-6-(3-氯丙氧基)-7-甲氧基喹唑啉

参考文献

Holladay, Mark W.; Campbell, Brian T.; Rowbottom, Martin W.; Chao, Qi; Sprankle, Kelly G.; Lai, Andiliy G.; Abraham, Sunny; Setti, Eduardo; Faraoni, Raffaella; Tran, Lan; Armstrong, Robert C.; Gunawardane, Ruwanthi N.; Gardner, Michael F.; Cramer, Merryl D.; Gitnick, Dana; Ator, Mark A.; Dorsey, Bruce D.; Ruggeri, Bruce R.; Williams, Michael; Bhagwat, Shripad S.; James, Joyce
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5342 - 5346

6702-50-73-羟基-4-甲氧基苯甲酸甲酯+

75-03-6碘乙烷

97966-31-93-乙氧基-4-甲氧基苯甲酸甲酯

参考文献

Wissner; Berger; Boschelli; Brawner Floyd Jr.; Greenberger; Gruber; Johnson; Mamuya; Nilakantan; Reich; Shen; Tsou; Upeslacis; Yu Fen Wang; Wu; Ye; Zhang
Journal of Medicinal Chemistry, 2000 , vol. 43, # 17 p. 3244 - 3256

6702-50-73-羟基-4-甲氧基苯甲酸甲酯+

100-39-0溴化苄

57535-57-6+

97966-31-93-乙氧基-4-甲氧基苯甲酸甲酯

参考文献

Fujisawa Pharmaceutical Co., Ltd.
Patent: US6384080 B1, 2002 ;

6702-50-73-羟基-4-甲氧基苯甲酸甲酯

574745-97-44-氯-7-甲氧基喹唑啉-6-醇

参考文献

Pham, Helen Trinh; Hanson, Robert N.; Olmsted, Sandra L.; Kozhushnyan, Anton; Visentin, Adam; Weglinsky, Paul J.; Massero, Chris; Bailey, Kristen
Tetrahedron Letters, 2011 , vol. 52, # 10 p. 1053 - 1056

6702-50-73-羟基-4-甲氧基苯甲酸甲酯+

100-39-0溴化苄

57535-57-6

参考文献

Tasler, Stefan; Mueller, Oliver; Wieber, Tanja; Herz, Thomas; Pegoraro, Stefano; Saeb, Wael; Lang, Martin; Krauss, Rolf; Totzke, Frank; Zirrgiebel, Ute; Ehlert, Jan E.; Kubbutat, Michael H.G.; Schaechtele, Christoph
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6728 - 6737