1,3-二氯-2-异氰基苯合成路线 （共 3 条）
反应条件
4-methyl-morpholine; trichloromethyl chloroformate in dichloromethane
T=-30°C; 1 h;
参考文献
Kamer, Paul C. J.; Nolte, Roeland J. M.; Drenth, Wiendelt
Journal of the American Chemical Society, 1988 , vol. 110, # 20 p. 6818 - 6825
反应条件
lithium perchlorate in N,N-dimethyl-formamide
T=15°C; Reduction; Electrolysis;
参考文献
Guirado, Antonio; Zapata, Andres; Gomez, Jesus L.; Trabalon, Luis; Galvez, Jesus
Tetrahedron, 1999 , vol. 55, # 31 p. 9631 - 9640
反应条件
1: 85 percent / acetic anhydride / CH2Cl2 / 20 h / Ambient temperature
2: 65 percent / N-methylmorpholine, diphosgene / CH2Cl2 / 1 h / -30 °C
View Scheme
参考文献
Kamer, Paul C. J.; Nolte, Roeland J. M.; Drenth, Wiendelt
Journal of the American Chemical Society, 1988 , vol. 110, # 20 p. 6818 - 6825
