1,1,4,4,6-五甲基-1,2,3,4-四氢化萘合成路线 （共 36 条）
反应条件
1: 85 percent / Br2; AlCl3 / CH2Cl2 2: n-BuLi / tetrahydrofuran; hexane / 3 h / -78 - 20 °C 3: 2.38 g / aq. HCl / tetrahydrofuran / 2 h / 20 °C 4: 88 percent / Pd(OAc)2; P(o-Tol)3; Et3N / dimethylformamide / 2 h / 50 °C 5: H2O View Scheme
参考文献
Zhang; Badea; Enyeart; Berger; Mais; Boehm
Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 7 p. 701 - 712
反应条件
1: AlCl3 / CH2Cl2; nitromethane / 24 h / 15 - 30 °C 2: NaNH2 / tetrahydrofuran 3: 65 percent / Et2Zn / CH2Cl2 View Scheme
参考文献
Faul; Ratz; Sullivan; Trankle; Winneroski
Journal of Organic Chemistry, 2001 , vol. 66, # 17 p. 5772 - 5782
反应条件
1: 50 percent / HNO3; H2SO4 / -10 °C 2: 48 percent / H2 / Pd/C / ethanol View Scheme
参考文献
Kagechika, Hiroyuki; Kawachi, Emiko; Hashimoto, Yuichi; Himi, Toshiyuki; Shudo, Koichi
Journal of Medicinal Chemistry, 1988 , vol. 31, # 11 p. 2182 - 2192
反应条件
ammonium cerium(IV) nitrate; acetic acid in water
T=100°C; 1 h;
参考文献
Ates-Alagoz, Zeynep; Buyukbingol, Erdem
Heterocyclic Communications, 2001 , vol. 7, # 5 p. 455 - 460
反应条件
ammonium cerium(IV) nitrate; acetic acid
T=100°C; 0.25 h;
参考文献
Dawson; Hobbs; Derdzinski; Chao; Frenking; Loew; Jetten; Napoli; Williams; Sani; Wille Jr.; Schiff
Journal of Medicinal Chemistry, 1989 , vol. 32, # 7 p. 1504 - 1517
反应条件
aluminium trichloride
参考文献
Wood,T.F. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 2248 - 2255
