4-(2-羟基-3-(异丙基氨基)丙氧基)-苯氨基甲酸乙酯合成路线 （共 5 条）
反应条件
1: NaOH / H2O / 24 h / Ambient temperature
2: methanol / Heating
View Scheme
参考文献
Kettmann; Csollei; Racanska; Svec
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 9 p. 843 - 851
反应条件
2: 21percent H2N-NH2*H2O, Raney-Ni / ethanol / Heating
3: 1) glacial acetic acid, 2) NaOH / 1) acetone, 1 h, 2) H2O
View Scheme
参考文献
Lehmann; Eckardt; Faust; Fiedler
Pharmazie, 1980 , vol. 35, # 5-6 p. 278 - 284
反应条件
1: 21percent H2N-NH2*H2O, Raney-Ni / ethanol / Heating
2: 1) glacial acetic acid, 2) NaOH / 1) acetone, 1 h, 2) H2O
View Scheme
参考文献
Lehmann; Eckardt; Faust; Fiedler
Pharmazie, 1980 , vol. 35, # 5-6 p. 278 - 284
反应条件
in methanol
Heating;
参考文献
Kettmann; Csollei; Racanska; Svec
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 9 p. 843 - 851
反应条件
sodium hydroxide; acetic acid
1) acetone, 1 h, 2) H2O; Yield given. Multistep reaction;
参考文献
Lehmann; Eckardt; Faust; Fiedler
Pharmazie, 1980 , vol. 35, # 5-6 p. 278 - 284
