2,3-二甲基-6-硝基苯酚合成路线 （共 10 条）
反应条件
sodium hydroxide; sodium tetrahydroborate; palladium on activated charcoal T=0°C;
参考文献
Bolognese, Adele; Correale, Gaetano; Manfra, Michele; Lavecchia, Antonio; Novellino, Ettore; Pepe, Stefano
Journal of Medicinal Chemistry, 2006 , vol. 49, # 17 p. 5110 - 5118
反应条件
ammonia; water; ammonium chloride
参考文献
Journal of the American Chemical Society, , vol. 72, p. 2034,2035
反应条件
nitrogen(IV) oxide in chloroform-d1
T=-60°C; Further byproducts given;
参考文献
Fischer, Alfred; Mathivanan, N.
Tetrahedron Letters, 1988 , vol. 29, # 16 p. 1869 - 1872
反应条件
1: trifluoroacetic anhydride, nitric acid / diethyl ether / 0.5 h / -60 °C
2: tetrahydrofuran
View Scheme
参考文献
Fischer, Alfred; Henderson, George N.; Sankararaman, S.
Canadian Journal of Chemistry, 1989 , vol. 67, p. 1244 - 1246
反应条件
nitric acid; acetic acid
参考文献
Holler; Huggett; Rathmann
Journal of the American Chemical Society, 1950 , vol. 72, p. 2034,2035
反应条件
nitrogen(IV) oxide in chloroform-d1
T=-60°C; Further byproducts given;
参考文献
Fischer, Alfred; Mathivanan, N.
Tetrahedron Letters, 1988 , vol. 29, # 16 p. 1869 - 1872
反应条件
nitric acid; acetic anhydride
T=-60°C;
参考文献
Cross, Gordon G.; Fischer, Alfred; Henderson, George N.; Smyth, Trevor A.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 1446 - 1451
反应条件
in tetrahydrofuran; diethyl ether
1 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Fischer, Alfred; Henderson, George N.; Sankararaman, S.
Canadian Journal of Chemistry, 1989 , vol. 67, p. 1244 - 1246
反应条件
in tetrahydrofuran
Yields of byproduct given;
参考文献
Fischer, Alfred; Henderson, George N.; Sankararaman, S.
Canadian Journal of Chemistry, 1989 , vol. 67, p. 1244 - 1246
反应条件
1: (i) aq. NaOH, MeOH, (ii) /BRN= 635994/, toluene
2: H2 / Raney-Ni / ethanol
View Scheme
参考文献
Zbiral,E. et al.
Monatshefte fuer Chemie, 1960 , vol. 91, p. 331 - 347
