7-碘-3,4-二氢异喹啉-1(2H)-酮合成路线

66491-03-07-氨基-3,4-二氢异喹啉-1(2H)-酮→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

Hutchinson, John H.; Cook, Jacquelynn J.; Brashear, Karen M.; Breslin, Michael J.; Glass, Joan D.; Gould, Robert J.; Halczenko, Wasyl; Holahan, Marie A.; Lynch, Robert J.; Sitko, Gary R.; Stranieri, Maria T.; Hartman, George D.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 23 p. 4583 - 4591

7681-65-4碘化亚铜+66491-03-07-氨基-3,4-二氢异喹啉-1(2H)-酮→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

NOVARTIS AG; Bock, Mark Gary; Gaul, Christoph; Gummadi, Venkateshwar Rao; Moebitz, Henrik; Sengupta, Saumitra
Patent: US2014/45872 A1, 2014 ;
Location in patent: Paragraph 0579 ;

1196-38-93,4-二氢异喹啉-1(2H)-酮→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

Girard; Atkinson; Belanger; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3220 - 3234

22245-96-17-硝基-3,4-二氢-2H-异喹啉-1-酮→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

Girard; Atkinson; Belanger; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3220 - 3234

6552-60-91,2,3,4-四氢异喹啉-1-硫酮→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

Girard; Atkinson; Belanger; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3220 - 3234

2257-09-22-苯基乙基异硫代氰酸酯→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

Girard; Atkinson; Belanger; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3220 - 3234

86288-79-1→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

Girard; Atkinson; Belanger; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3220 - 3234

6970-83-8n-苯乙基氨基甲酸乙酯→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

NOVARTIS AG; BOCK, Mark G.; GAUL, Christoph; GUMMADI, Venkateshwar Rao; MOEBITZ, Henrik; SENGUPTA, Saumitra
Patent: WO2012/35078 A1, 2012 ;
WO 2012/035078 A1

64-04-02-苯乙胺→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮

参考文献

NOVARTIS AG; Bock, Mark Gary; Gaul, Christoph; Gummadi, Venkateshwar Rao; Moebitz, Henrik; Sengupta, Saumitra
Patent: US2014/45872 A1, 2014 ;

66491-03-07-氨基-3,4-二氢异喹啉-1(2H)-酮→66491-04-17-碘-3,4-二氢异喹啉-1(2H)-酮+1196-38-93,4-二氢异喹啉-1(2H)-酮

参考文献

Girard; Atkinson; Belanger; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 19 p. 3220 - 3234