(6-溴-1,3-苯并二氧代l-5-基)甲醇合成路线 (共 37 条)
反应条件
N-bromosuccinmide in dichloromethane T=5°C; 2 h;
参考文献
Rigby, James H.; Cavezza, Alexandre; Heeg, Mary Jane
Journal of the American Chemical Society, 1998 , vol. 120, # 15 p. 3664 - 3670
反应条件
sodium tetrahydroborate in ethanol T=0 - 20°C; 16 h;
参考文献
Beck, Daniel E.; Agama, Keli; Marchand, Christophe; Chergui, Adel; Pommier, Yves; Cushman, Mark
Journal of Medicinal Chemistry, 2014 , vol. 57, # 4 p. 1495 - 1512
反应条件
sodium methylate in dimethyl sulfoxide T=130°C; 0.05 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 42, # 3 p. 500 - 511
反应条件
sodium methylate in dimethyl sulfoxide T=150°C; 0.0194444 h;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 28, # 4 p. 1287 - 1293
反应条件
2,2,6,6-tetramethylpiperidinyl-lithium in tetrahydrofuran T=-78 - 20°C; 0.666667 h;
参考文献
Tetrahedron, , vol. 52, # 4 p. 1389 - 1398
反应条件
1: 70 percent / bromine, iodine / acetic acid; CS2 2: 46 g / sodium borohydride / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 55, # 5 p. 1471 - 1475
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5885,5889
反应条件
sodium methylate; dimethyl sulfoxide T=150°C; 0.0194444 h;
参考文献
Heterocycles, , vol. 31, # 6 p. 1067 - 1076
反应条件
sodium methylate; dimethyl sulfoxide; benzyl alcohol T=150°C; 0.0194444 h;
参考文献
Heterocycles, , vol. 31, # 6 p. 1067 - 1076
反应条件
in dimethyl sulfoxide T=150°C; 0.0194444 h;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 28, # 4 p. 1287 - 1293