5-三氟甲基-2’-脱氧胞苷合成路线 （共 4 条）
反应条件
tert.-butylhydroperoxide in water T=0 - 20°C; 3 h;
参考文献
Musumeci, Domenica; Irace, Carlo; Santamaria, Rita; Montesarchio, Daniela
MedChemComm, 2013 , vol. 4, # 10 p. 1405 - 1410
参考文献
Kobayashi, Yoshiro; Yamamoto, Kenjiro; Asai, Toyohira; Nakano, Masanori; Kumadaki, Itsumaro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2755 - 2761
反应条件
1: 62 percent / iodine, silver trifluoroacetate / CH2Cl2 / 5 h / Ambient temperature 2: 1.) copper powder / 1.) HMPA, 120 deg C, 2.5 h, 2.) 45 deg C, 12 h 3: 69 percent / methanolic ammonia / 5 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2755 - 2761
反应条件
1: 1.) copper powder / 1.) HMPA, 120 deg C, 2.5 h, 2.) 45 deg C, 12 h 2: 69 percent / methanolic ammonia / 5 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2755 - 2761
