2-(4-氨基苯基)乙酰胺合成路线 （共 8 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol
T=20°C; P=760.051 Torr; 24 h;
参考文献
RIB-X PHARMACEUTICALS, INC.
Patent: WO2005/85266 A2, 2005 ;
Location in patent: Page/Page column 231 ;
反应条件
ammonia; sodium chloride in water
T=22°C; 16 h;
参考文献
INTERNATIONAL FLAVORS and FRAGRANCES INC.
Patent: EP2246323 A1, 2010 ;
Location in patent: Page/Page column 8 ;
反应条件
choline chloride*2ZnCl2 in water
T=100°C; 9 h; Green chemistry;
参考文献
Patil, Umakant B.; Singh, Abhilash S.; Nagarkar, Jayashree M.
RSC Advances, 2014 , vol. 4, # 3 p. 1102 - 1106
反应条件
hydrogenchloride in methanol
参考文献
AtraZeneca AB
Patent: US2004/101864 A1, 2004 ;
参考文献
AtraZeneca AB
Patent: US2004/101864 A1, 2004 ;
参考文献
Jacobs; Heidelberger
Journal of the American Chemical Society, 1917 , vol. 39, p. 1437
反应条件
1: HNO3+H2SO4
2: aqueous ammonium sulfide
View Scheme
参考文献
Purgotti
Gazzetta Chimica Italiana, 1890 , vol. 20, p. 596
反应条件
immobilized activated nitrilase in water
Ambient temperatureeffect of β-cyclodextrin; Rate constant;
参考文献
Geresh, Shimona; Giron, Yakir; Gilboa, Ygal; Glaser, Robert
Tetrahedron, 1993 , vol. 49, # 44 p. 10099 - 10102
