1-(2-乙酰基吩噻嗪-10-基)乙酮合成路线 （共 10 条）
反应条件
1: With iodine in pyridine T=20 - 100°C; 20.25 h; 2: With sodium hydroxide in water T=100°C; 1 h; 3: With hydrogenchloride in water
参考文献
Auvin, Serge; Chabrier De Lassauniere, Pierre-Etienne
Patent: US2005/222045 A1, 2005 ;
Location in patent: Page/Page column 11 ;
参考文献
Chan, Cecil; Yin, Hong; Garforth, Jacqui; McKie, James H.; Jaouhari, Rabih; Speers, Peter; Douglas, Kenneth T.; Rock, Peter J.; Yardley, Vanessa; Croft, Simon L.; Fairlamb, Alan H.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 2 p. 148 - 156
反应条件
1: aq. HCl / ethanol 2: NaH View Scheme
参考文献
Chan, Cecil; Yin, Hong; Garforth, Jacqui; McKie, James H.; Jaouhari, Rabih; Speers, Peter; Douglas, Kenneth T.; Rock, Peter J.; Yardley, Vanessa; Croft, Simon L.; Fairlamb, Alan H.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 2 p. 148 - 156
反应条件
in toluene
2.75 h; Heating / reflux;
参考文献
Auvin, Serge; Chabrier De Lassauniere, Pierre-Etienne
Patent: US2005/222045 A1, 2005 ;
Location in patent: Page/Page column 11 ;
反应条件
1: toluene / 2 h / Heating
2: AlCl3 / CS2 / 6 h / Heating
View Scheme
参考文献
Chan, Cecil; Yin, Hong; Garforth, Jacqui; McKie, James H.; Jaouhari, Rabih; Speers, Peter; Douglas, Kenneth T.; Rock, Peter J.; Yardley, Vanessa; Croft, Simon L.; Fairlamb, Alan H.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 2 p. 148 - 156
反应条件
carbon disulfide; aluminium trichloride
参考文献
Baltzly et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 2673,2677
反应条件
carbon disulfide; aluminium trichloride
参考文献
Baltzly et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 2673,2677
反应条件
1: aq. KOH / ethanol / 2 h / Heating
2: benzene / 7 h / Heating
View Scheme
参考文献
Profft,E.; Kasper,F.
Arzneimittel Forschung, 1962 , vol. 12, p. 48 - 52
反应条件
1: aq. KOH / ethanol / 2 h / Heating
2: benzene / 7 h / Heating
View Scheme
参考文献
Profft,E.; Kasper,F.
Arzneimittel Forschung, 1962 , vol. 12, p. 48 - 52
反应条件
carbon disulfide; aluminium trichloride
参考文献
Cauquil; Casadevall
Bulletin de la Societe Chimique de France, 1955 , p. 768,781
