2,6-二甲基-1-茚满酮合成路线 （共 10 条）
反应条件
AlCl3, aluminium chloride in dichloromethane
T=0°C; 4 h; Heating / reflux;
参考文献
EXXONMOBIL CHEMICAL PATENTS INC.
Patent: WO2007/70041 A1, 2007 ;
Location in patent: Page/Page column 106 ;
反应条件
polyphosphoric acid
T=80°C; Friedel-Crafts Acylation; 12 h;
参考文献
Wang, Zhi-Gang; Chen, Liqun; Chen, Jiebo; Zheng, Jian-Feng; Gao, Weiwei; Zeng, Zhiping; Zhou, Hu; Zhang, Xiao-Kun; Huang, Pei-Qiang; Su, Ying
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 632 - 648
反应条件
aluminium trichloride in toluene
Heating;
参考文献
Pinnick, Harold W.; Brown, Stephen P.; McLean, Elizabeth A.; Zoller, Linwood W.
Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3758 - 3760
反应条件
1: 72 percent / AlCl3 / 0 - 20 °C
2: 42 percent / methanol / 16 h / Irradiation
View Scheme
参考文献
Bergmark, William R.; Barnes, Curtis; Clark, Jeffrey; Paparian, Seth; Marynowski, Susan
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5612 - 5615
反应条件
in methanol
16 h; Irradiation;
参考文献
Bergmark, William R.; Barnes, Curtis; Clark, Jeffrey; Paparian, Seth; Marynowski, Susan
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5612 - 5615
反应条件
1: K2CO3 / dimethylformamide / 10 h / 150 °C
2: concd. HCl / acetic acid / 24 h / Heating
3: 1.12 g / polyphosphoric acid / 3 h / 100 °C
View Scheme
参考文献
Fukuoka, Masamichi; Yoshihira, Kunitoshi; Natori, Shinsaku; Mihashi, Kunihide; Nishi, Masatoshi
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3113 - 3128
反应条件
1: palladium 10 on activated carbon; hydrogen / methanol / 24 h / 7600.51 Torr
2: polyphosphoric acid / 12 h / 80 °C
View Scheme
参考文献
Wang, Zhi-Gang; Chen, Liqun; Chen, Jiebo; Zheng, Jian-Feng; Gao, Weiwei; Zeng, Zhiping; Zhou, Hu; Zhang, Xiao-Kun; Huang, Pei-Qiang; Su, Ying
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 632 - 648
反应条件
1.1: potassium carbonate / 0.08 h / 0 °C
1.2: 12 h / 160 - 180 °C
2.1: palladium 10 on activated carbon; hydrogen / methanol / 24 h / 7600.51 Torr
3.1: polyphosphoric acid / 12 h / 80 °C
View Scheme
参考文献
Wang, Zhi-Gang; Chen, Liqun; Chen, Jiebo; Zheng, Jian-Feng; Gao, Weiwei; Zeng, Zhiping; Zhou, Hu; Zhang, Xiao-Kun; Huang, Pei-Qiang; Su, Ying
European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 632 - 648
反应条件
in tert-butyl alcohol
16 h; Irradiationother solvent; Quantum yield;
参考文献
Bergmark, William R.; Barnes, Curtis; Clark, Jeffrey; Paparian, Seth; Marynowski, Susan
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5612 - 5615
参考文献
Bergmark, William R.; Barnes, Curtis; Clark, Jeffrey; Paparian, Seth; Marynowski, Susan
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5612 - 5615
