2-苯基乙基丙二酸二乙酯合成路线 (共 27 条)
反应条件
sodium hydride in tetrahydrofuran Heating;
参考文献
Abraham, D. J.; Kennedy, P. E.; Mehanna, A. S.; Patwa, D. C.; Williams, F. L.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 967 - 978
反应条件
hydrogenchloride in tetrahydrofuran; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; hexane; mineral oil
参考文献
Merck and Co., Inc.
Patent: US5629343 A1, 1997 ;
US 5629343 A
反应条件
potassium tert-butylate in N-methyl-acetamide; water
参考文献
US5677297 A1, ;
US 5677297 A
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; samarium diiodide in tetrahydrofuran; tert-butyl alcohol 0.166667 h; Ambient temperature;
参考文献
Yamashita; Okuyama; Ohhara; Kawasaki; Sakai; Nakata; Kawabe; Kusumoto; Ohta
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 12 p. 2075 - 2081
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene 0.5 h; Ambient temperatureIrradiation;
参考文献
Baciocchi, Enrico; Giese, Bernd; Farshchi, Hassan; Ruzziconi, Renzo
Journal of Organic Chemistry, 1990 , vol. 55, # 22 p. 5688 - 5691
反应条件
1: 100 - 110 °C / Einleiten von HBr 2: toluene View Scheme
参考文献
Annales de Chimie (Cachan, France), , vol. <11> 9, p. 5,82
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 202, p. 1679
参考文献
Bulletin de la Societe Chimique de France, , p. 219 - 230
Chemische Berichte, , vol. 57, p. 1213
Journal of the American Chemical Society, , vol. 46, p. 2845
Chemische Berichte, , vol. 39, p. 2210
反应条件
sodium ethanolate 4 h; Reflux;
参考文献
Inorganic Chemistry, , vol. 49, # 7 p. 3261 - 3270
反应条件
1: potassium ethylate; diethyl ether 2: bei der Destillation View Scheme
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 109, p. 126,139
参考文献
Tetrahedron Letters, , p. 997 - 1000