(S)-(+)-1-氨基乙基膦酸合成路线 （共 14 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Oesapay, G; Csiba, A
European Journal of Medicinal Chemistry, 1993 , vol. 28, # 5 p. 355 - 361
反应条件
hydrogenchloride in water 15 h; Heating;
参考文献
Huber, Rolf; Knierzinger, Andreas; Obrecht, Jean-Pierre; Vasella, Andrea
Helvetica Chimica Acta, 1985 , vol. 68, p. 1730 - 1747
反应条件
hydrogen bromide in acetic acid 20 h; Heating;
参考文献
Kafarski, Pawel; Lejczak, Barbara; Szewczyk, Jerzy
Canadian Journal of Chemistry, 1983 , vol. 61, p. 2425 - 2430
反应条件
hydrogenchloride T=106°C; 24 h;
参考文献
Atherton; Hassall; Lambert
Journal of Medicinal Chemistry, 1986 , vol. 29, # 1 p. 29 - 40
反应条件
72 h; Ambient temperaturepenicillin acylase in 0.01 M phosphate buffer, pH 7.0;
参考文献
Solodenko, Vladimir A.; Belik, Michail Y.; Galushko, Sergei V.; Kukhar, Valeri P.; Kozlova, Elena V.; et al.
Tetrahedron: Asymmetry, 1993 , vol. 4, # 9 p. 1965 - 1968
参考文献
Phosphorus and Sulfur and the Related Elements, , vol. 18, p. 393 - 396
反应条件
hydrogenchloride; 2) C 1) 24 h, reflux; 2) H2O, 10 min; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Liebigs Annalen der Chemie, , p. 45 - 50
反应条件
hydrogenchloride; methyloxirane 1) reflux, 20h 2a) EtOH, 20 deg C, 1h 2b) 2 deg C, 1h; Yield given. Multistep reaction;
参考文献
Synthesis, , # 2 p. 132 - 134
反应条件
hydrogenchloride; n-butyllithium; 2,4,6-triisopropyl-benzenesulfonyl azide; hydrogen 1.) THF, hexane, -78 deg C, 30 min, 2.) H2O, 25 deg C, 3.) EtOAc, RT, 1 h; Yield given. Multistep reaction;
参考文献
Synthesis, , # SPEC. ISS. p. 1272 - 1274
反应条件
Cuninghamella echinulata DSM 1905 pH=6.11; 48 h; Resolution of racemateMicrobiological reactionaq. phosphate buffer; optical yield given as percent eeenantioselective reaction;
参考文献
Molecules, , vol. 16, # 7 p. 5896 - 5904
