1-(6,7-二甲氧基-1-苯基-3,4-二氢-1H-异喹啉-2-基)-乙酮合成路线 （共 8 条）
反应条件
toluene-4-sulfonic acid in dichloromethane
T=20°C; 0.5 h;
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Aladjov, Dimo; Stefanova, Iliyana; Zagorchev, Plamen
Molecules, 2011 , vol. 16, # 8 p. 7019 - 7042
反应条件
2,6-dimethylpyridine; gold(III) chloride; silver trifluoromethanesulfonate in acetonitrile
T=20°C; 12 h;
参考文献
Youn, So Won
Journal of Organic Chemistry, 2006 , vol. 71, # 6 p. 2521 - 2523
反应条件
1: toluene / 3 h / Heating
2: trifluoroacetic acid / 1.5 h / Heating
3: 1.5 h / Heating
View Scheme
参考文献
Gitto, Rosaria; Barreca, Maria Letizia; De Luca, Laura; De Sarro, Giovambattista; Ferreri, Guido; Quartarone, Silvana; Russo, Emilio; Constanti, Andrew; Chimirri, Alba
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 197 - 200
反应条件
1: toluene / 3 h / Heating
2: trifluoroacetic acid / 1.5 h / Heating
3: 1.5 h / Heating
View Scheme
参考文献
Gitto, Rosaria; Barreca, Maria Letizia; De Luca, Laura; De Sarro, Giovambattista; Ferreri, Guido; Quartarone, Silvana; Russo, Emilio; Constanti, Andrew; Chimirri, Alba
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 197 - 200
反应条件
1: polyphosphoric acid / dichloromethane / 2 h / 80 °C
2: methanol; sodium tetrahydroborate / 0.5 h / 20 °C
3: toluene-4-sulfonic acid / dichloromethane / 0.5 h / 20 °C
View Scheme
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Aladjov, Dimo; Stefanova, Iliyana; Zagorchev, Plamen
Molecules, 2011 , vol. 16, # 8 p. 7019 - 7042
反应条件
1: methanol; sodium tetrahydroborate / 0.5 h / 20 °C
2: toluene-4-sulfonic acid / dichloromethane / 0.5 h / 20 °C
View Scheme
参考文献
Ivanov, Iliyan; Nikolova, Stoyanka; Aladjov, Dimo; Stefanova, Iliyana; Zagorchev, Plamen
Molecules, 2011 , vol. 16, # 8 p. 7019 - 7042
反应条件
1: trifluoroacetic acid / 1.5 h / Heating
2: 1.5 h / Heating
View Scheme
参考文献
Gitto, Rosaria; Barreca, Maria Letizia; De Luca, Laura; De Sarro, Giovambattista; Ferreri, Guido; Quartarone, Silvana; Russo, Emilio; Constanti, Andrew; Chimirri, Alba
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 197 - 200
参考文献
Gitto, Rosaria; Barreca, Maria Letizia; De Luca, Laura; De Sarro, Giovambattista; Ferreri, Guido; Quartarone, Silvana; Russo, Emilio; Constanti, Andrew; Chimirri, Alba
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 197 - 200
