2,4-二甲基苯乙基乙醇合成路线 （共 17 条）
反应条件
potassium hydroxide T=200°C;
参考文献
Annales de Chimie (Cachan, France), , vol. <11>6, p. 249,303
反应条件
1: With benzo[1,3,2]dioxaborole; rhodium complex 2 in toluene
T=20°C; Addition; Hydroboration; 2 h;
2: With sodium hydroxide; water; dihydrogen peroxide in toluene
T=20°C; Oxidation; 2 h; Title compound not separated from byproducts;
参考文献
Doucet, Henri; Fernandez, Elena; Layzell, Timothy P.; Brown, John M.
Chemistry - A European Journal, 1999 , vol. 5, # 4 p. 1320 - 1330
反应条件
(i) Mg, Et2O, (ii) /BRN= 102378/; Multistep reaction;
参考文献
Cagniant,P. et al.
Bulletin de la Societe Chimique de France, 1960 , p. 1798 - 1807
反应条件
sodium tetrahydroborate
Yield given;
参考文献
Yamaguchi, Masahiko; Kido, Yoshiyuki; Hayashi, Akio; Hirama, Masahiro
Angewandte Chemie (International Edition in English), 1997 , vol. 36, # 12 p. 1313 - 1315
反应条件
sodium cyanoborohydride; zinc(II) iodide in 1,2-dichloro-ethane
16 h; Heating;
参考文献
Finkielsztein; Aguirre; Lantano; Alesso; Moltrasio Iglesias
Synthetic Communications, 2004 , vol. 34, # 5 p. 895 - 901
反应条件
1: AlCl3 / CS2 / 0.5 h / Heating
2: 22 percent / sodium cyanoborohydride; zinc iodide / 1,2-dichloro-ethane / 16 h / Heating
View Scheme
参考文献
Finkielsztein; Aguirre; Lantano; Alesso; Moltrasio Iglesias
Synthetic Communications, 2004 , vol. 34, # 5 p. 895 - 901
反应条件
1: 85 percent / m-chloroperbenzoic acid; NaHCO3 / CH2Cl2 / 4.5 h / 0 - 20 °C
2: CF3CO2H; H2O / CH2Cl2 / 12 h / 20 °C
3: 40 mg / NaBH4 / methanol / 0.17 h / 0 °C
View Scheme
参考文献
Kido, Yoshiyuki; Yoshimura, Satoru; Yamaguchi, Masahiko; Uchimaru, Tadafumi
Bulletin of the Chemical Society of Japan, 1999 , vol. 72, # 7 p. 1445 - 1458
反应条件
1: CF3CO2H; H2O / CH2Cl2 / 12 h / 20 °C
2: 40 mg / NaBH4 / methanol / 0.17 h / 0 °C
View Scheme
参考文献
Kido, Yoshiyuki; Yoshimura, Satoru; Yamaguchi, Masahiko; Uchimaru, Tadafumi
Bulletin of the Chemical Society of Japan, 1999 , vol. 72, # 7 p. 1445 - 1458
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Bost et al.
Journal of Organic Chemistry, 1957 , vol. 22, p. 51,54
反应条件
1: 67 percent / m-chloroperbenzoic acid; NaHCO3 / CH2Cl2 / 4.5 h / 0 - 20 °C
2: CF3CO2H; H2O / CH2Cl2 / 12 h / 20 °C
3: 40 mg / NaBH4 / methanol / 0.17 h / 0 °C
View Scheme
参考文献
Kido, Yoshiyuki; Yoshimura, Satoru; Yamaguchi, Masahiko; Uchimaru, Tadafumi
Bulletin of the Chemical Society of Japan, 1999 , vol. 72, # 7 p. 1445 - 1458
