1-(6-甲基吡啶-2-基)丙酮合成路线 （共 10 条）
反应条件
diethyl ether; methyl acetate
参考文献
Goldberg; Levine
Journal of the American Chemical Society, 1952 , vol. 74, p. 5217
参考文献
Goldberg; Levine
Journal of the American Chemical Society, 1952 , vol. 74, p. 5217
反应条件
diethyl ether; phenyllithium
Weiteren Erwaermen mit Acetonitril in Aether und anschliessenden Behandeln mit wss.HCl;
参考文献
Burger; Ullyot
Journal of Organic Chemistry, 1947 , vol. 12, p. 342,351
反应条件
[Pd(η3-1-Ph-allyl)(μ-Cl)]2; 2-methoxy-6-(N-methyl-N-phenyl-amino)phenyl(dicyclohexyl)phosphine; caesium carbonate
T=90°C; 13 h; Inert atmosphereSchlenk techniqueSealed tube; Overall yield = 73 percent; Overall yield = 109.5 mg;
参考文献
Li, Pengbin; Lue, Bo; Fu, Chunling; Ma, Shengming
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 7 p. 1255 - 1259
反应条件
lithium diisopropyl amide
1.) ether, 0 deg C, 8 min, 2.) -78 deg C to r.t.; Multistep reaction;
参考文献
Paine III, John B.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1463 - 1465
反应条件
formic acid
Erwaermen des Reaktionsprodukts mit konz. wss. HCl;
参考文献
Burger; Ullyot
Journal of Organic Chemistry, 1947 , vol. 12, p. 342,351
反应条件
hydrogen; platinum(IV) oxide in acetic acid
Further byproducts given;
参考文献
Brown, W. Vance; Moore, Barry P.
Australian Journal of Chemistry, 1982 , vol. 35, # 6 p. 1255 - 1261
反应条件
Pd-BaSO4; perchloric acid; acetic acid
Hydrogenation;
参考文献
Graef et al.
Journal of Organic Chemistry, 1946 , vol. 11, p. 257,263
反应条件
potassium hydroxide; hydrazine hydrate
1.) methanol, r.t., overnight, 2.) diethylene glycol, water, reflux; Multistep reaction. Yields of byproduct given;
参考文献
Paine III, John B.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1463 - 1465
反应条件
potassium hydroxide; hydrazine hydrate
1.) methanol, r.t., overnight, 2.) diethylene glycol, water, reflux; Multistep reaction. Yields of byproduct given;
参考文献
Paine III, John B.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1463 - 1465
