1: benzo[b]thiophene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: With zinc(II) chloride in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere; 3: 3-bromo-benzo[b]-thiophene With XPhos G3; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in tetrahydrofuran; hexane T=20°C; Negishi Coupling; 12 h; Inert atmosphere;

phosphorus pentoxide; 1,2-dichloro-benzene

1: tetrachloromethane; bromine 2: pyridine 3: phosphorus (V)-oxide; 1,2-dichloro-benzene View Scheme

1: pyridine 2: phosphorus (V)-oxide; 1,2-dichloro-benzene View Scheme

T=260°C;

暂无反应条件数据

anschliessend mit Kupfer(II)-chlorid;