S-(+)-N-去甲基美芬妥英合成路线 （共 11 条）
反应条件
in propan-1-ol; 1,2-dichloro-ethane T=25°C; HPLC chiral separation by derivative of N,N'-2,6-pyridinediylbis<(S)-2-phenylbutanamide>;
参考文献
Journal of the American Chemical Society, , vol. 108, # 12 p. 3310 - 3318
反应条件
1: aqueous sulfuric acid 2: hydrogen chloride; ethanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 54, p. 4697,4699
反应条件
1: ueber das Chinin-Salz 2: aqueous sulfuric acid 3: hydrogen chloride; ethanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 54, p. 4697,4699
参考文献
DE574657 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 19, p. 1204
Journal of the American Chemical Society, , vol. 54, p. 4697,4699
反应条件
1: H2O 2: brucine View Scheme
参考文献
Journal of the American Chemical Society, , vol. 54, p. 4697,4699
反应条件
1: hydrogen chloride; ethanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 54, p. 4697,4699
反应条件
1: NH3 / H2O / 0 °C 2: 20percent aq. HCl / 0.25 h / Heating View Scheme
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 313, # 6 p. 538 - 543
参考文献
DE574657 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 19, p. 1204
Journal of the American Chemical Society, , vol. 54, p. 4697,4699
参考文献
DE574657 , ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 19, p. 1204
Journal of the American Chemical Society, , vol. 54, p. 4697,4699
反应条件
hydrogenchloride 0.25 h; Heating; Yield given. Yields of byproduct given;
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 313, # 6 p. 538 - 543
