反应条件
1: thionyl chloride / 1,2-dimethoxy-ethane; CH2Cl2 / Heating
2: 78 percent / NH3, triethylamine, 4-(dimethylamino)pyridine / diethyl ether / a) RT, 2 h, b) reflux, 2 h
View Scheme
参考文献
Albright, J. Donald; DeVries, Vern G.; Du, Mila T.; Largis, Elwood E.; Miner, Thomas G.; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1393 - 1411
