(8beta)-9,10-二去氢-N,N-二乙基-6-(2-丙烯基)-麦角灵-8-甲酰胺合成路线 （共 4 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=25°C; 0.5 h;
参考文献
Hoffman; Nichols
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1252 - 1255
反应条件
1: 61 percent / Zn / acetic acid; H2O / 4 h / Heating
2: 88 percent / K2CO3 / dimethylformamide / 0.5 h / 25 °C
View Scheme
参考文献
Hoffman; Nichols
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1252 - 1255
反应条件
1: 71 percent / CCl4; CHCl3 / 6 h / Heating
2: 61 percent / Zn / acetic acid; H2O / 4 h / Heating
3: 88 percent / K2CO3 / dimethylformamide / 0.5 h / 25 °C
View Scheme
参考文献
Hoffman; Nichols
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1252 - 1255
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C; 0.5 h;
参考文献
Stachulski, Andrew V.; Nichols, David E.; Scheinmann, Feodor
Journal of Chemical Research - Part S, 1996 , # 1 p. 30 - 31
