1: LiNH2, NH3 (liquid)
2: 80 percent / Ph3P, Br2 (5.5 M in CCl4), pyridine / CH2Cl2 / 2 h / Ambient temperature
3: NaH / 1) DMF, 0-60 deg C, 2) 4 h, 60 deg C
4: LiCl*H2O, H2O / 4 h / 160 - 165 °C
5: 90 percent / LAH / diethyl ether
6: 82 percent / Na/NH3 / tetrahydrofuran / 4 h / -78 °C
View Scheme
参考文献
Chattopadhyay, S.; Mamdapur, V. R.; Chadha, M. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 6 p. 580 - 582
1: NaH / 1) DMF, 0-60 deg C, 2) 4 h, 60 deg C
2: LiCl*H2O, H2O / 4 h / 160 - 165 °C
3: 90 percent / LAH / diethyl ether
4: 82 percent / Na/NH3 / tetrahydrofuran / 4 h / -78 °C
View Scheme
参考文献
Chattopadhyay, S.; Mamdapur, V. R.; Chadha, M. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 6 p. 580 - 582
Chattopadhyay, S.; Mamdapur, V. R.; Chadha, M. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 6 p. 580 - 582
1: LiCl*H2O, H2O / 4 h / 160 - 165 °C
2: 90 percent / LAH / diethyl ether
3: 82 percent / Na/NH3 / tetrahydrofuran / 4 h / -78 °C
View Scheme
参考文献
Chattopadhyay, S.; Mamdapur, V. R.; Chadha, M. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 6 p. 580 - 582
