3-(1,2,3,6-四氢吡啶-4-基)-1H-吲哚合成路线 （共 12 条）
反应条件
sodium methylate in methanol 18 h; Heating / reflux;
参考文献
US2006/122206 A1, ;
Page/Page column 3 ;
US 20060122206 A1
反应条件
potassium hydroxide in methanol 5.5 h; Reflux;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 7 p. 2560 - 2564
反应条件
potassium hydroxide in methanol
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 3 p. 307 - 310
反应条件
in methanol; potassium hydroxide
反应条件
phosphoric acid in methanol; acetic acid
反应条件
in methanol; acetic acid
反应条件
di-tert-butyl dicarbonate in methanol 12 h;
参考文献
SCHERING CORPORATION
Patent: WO2004/831 A1, 2003 ;
Location in patent: Page 39 ;
WO 2004/000831 A1
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in methanol P=2250.18 Torr; 1 h;
参考文献
GRUeNENTHAL GMBH
Patent: WO2004/43949 A1, 2004 ;
Location in patent: Page/Page column 30 ;
反应条件
N-ethyl-N,N-diisopropylamine in dimethyl sulfoxide
T=150°C; 4 h;
参考文献
Venkatesan, Aranapakam M.; Dos Santos; Ellingboe, John; Evrard, Deborah A.; Harrison, Boyd L.; Smith, Deborah L.; Scerni, Rosemary; Hornby, Geoffrey A.; Schechter, Lee E.; Andree, Terrence H.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 824 - 827
反应条件
potassium carbonate in tetrahydrofuran; water; N,N-dimethyl-formamide
参考文献
Wyeth
Patent: US2002/187983 A1, 2002 ;
