3-(4-异丁基苯基)-丙酸合成路线 （共 11 条）
反应条件
potassium hydroxide; polyethylene glycol (PEG-400); potassium cyanide; nickel cyanide; cobalt(II) chloride in toluene T=90°C; P=760 Torr; 24 h;
参考文献
Tetrahedron Letters, , vol. 32, # 15 p. 1769 - 1770
反应条件
toluene-4-sulfonic acid; triphenylphosphine; lithium chloride; palladium on activated charcoal in water; butanone T=115°C; Carbonylation; P=40503.2 Torr; 4 h; Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 12 p. 1067 - 1068
反应条件
toluene-4-sulfonic acid; triphenylphosphine; lithium chloride; palladium in water; butanone T=115°C; Carbonylation; P=40503.2 Torr; 8 h; Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 12 p. 1067 - 1068
反应条件
toluene-4-sulfonic acid; triphenylphosphine; lithium chloride; palladium on activated charcoal in water; butanone T=115°C; Carbonylation; P=40503.2 Torr; 4 h; Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 12 p. 1067 - 1068
反应条件
TPPTS; toluene-4-sulfonic acid; lithium chloride; 2-PyCOO-Pd-OTs in water; toluene T=115°C; Dehydration; Carbonylation; P=40504.1 Torr; 5 h; Title compound not separated from byproducts.;
参考文献
Chemical Communications, , # 14 p. 1239 - 1240
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 2121 - 2126
反应条件
1: 86 percent / morpholine / 2 h / Heating 2: H2 / 20percent Pd/C / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 2121 - 2126
反应条件
1: 38 percent / aq. sodium hypochlorite / 12 h / Heating 2: borane / tetrahydrofuran / 3 h / Ambient temperature 3: 89 percent / pyridinium chlorochromate / CH2Cl2 / 3 h 4: 86 percent / morpholine / 2 h / Heating 5: H2 / 20percent Pd/C / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 2121 - 2126
反应条件
1: borane / tetrahydrofuran / 3 h / Ambient temperature 2: 89 percent / pyridinium chlorochromate / CH2Cl2 / 3 h 3: 86 percent / morpholine / 2 h / Heating 4: H2 / 20percent Pd/C / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 2121 - 2126
反应条件
1: 89 percent / pyridinium chlorochromate / CH2Cl2 / 3 h 2: 86 percent / morpholine / 2 h / Heating 3: H2 / 20percent Pd/C / methanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 11 p. 2121 - 2126
