4-(2-羟基乙基)-5-甲基-1,2-二氢-3H-吡唑-3-酮合成路线 （共 2 条）
反应条件
hydrazine hydrate in water Ring cleavage; cyclocondensation; 2 h; Heating;
参考文献
Zimmermann, Diane; Janin, Yves Louis; Brehm, Lotte; Braeuner-Osborne, Hans; Ebert, Bjarke; Johansen, Tommy Norskov; Madsen, Ulf; Krogsgaard-Larsen, Povl
European Journal of Medicinal Chemistry, 1999 , vol. 34, # 11 p. 967 - 976
反应条件
1: 62 percent HBr / 16 h / 80 °C
2: K2CO3 / dimethylsulfoxide-d6 / 2 h / 22 °C
View Scheme
参考文献
Zimmermann, Diane; Janin, Yves Louis; Brehm, Lotte; Braeuner-Osborne, Hans; Ebert, Bjarke; Johansen, Tommy Norskov; Madsen, Ulf; Krogsgaard-Larsen, Povl
European Journal of Medicinal Chemistry, 1999 , vol. 34, # 11 p. 967 - 976
