1: With potassium carbonate in water
T=10°C;
2: methylamine in water; acetonitrile
T=0 - 5°C;
3: 1-benzyl-piperazine; phenyl chloroformate With sodium hydroxide
more than 3 stages;
参考文献
Zhao, Matthew M.; Yin, Jingjun
Patent: US2004/23979 A1, 2004 ;
Location in patent: Page/Page column 10 ;
US 20040023979 A1