4-羟基-2,3,5,6-四氟苯甲酸合成路线 （共 13 条）
反应条件
1: TFP-OH With n-butyllithium in tetrahydrofuran; hexane T=-65°C; 1 h; 2: carbon dioxide in tetrahydrofuran; hexane T=-65 - 20°C; 3 h;
参考文献
Kang, Seok Ho; Luo, Jingdong; Ma, Hong; Barto, Richard R.; Frank, Curtis W.; Dalton, Larry R.; Jen, Alex K.-Y.
Macromolecules, 2003 , vol. 36, # 12 p. 4355 - 4359
反应条件
2: tert-butyl alcohol 3: KOH View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: FeCl3 / N,N-dimethyl-formamide 2: tert-butyl alcohol 3: KOH View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: N,N-dimethyl-formamide 2: tert-butyl alcohol 3: KOH View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: tert-butyl alcohol 2: KOH View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: FeCl3 / N,N-dimethyl-formamide 2: tert-butyl alcohol 3: KOH View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
1: pyridine / benzene 2: tert-butyl alcohol 3: KOH View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
反应条件
sodium hydroxide; water; zinc T=60°C; Substitution; Hydrodefluorination; 20 h; Title compound not separated from byproducts;
参考文献
Journal of Physical Chemistry A, , vol. 104, # 2 p. 352 - 361
反应条件
1: ethanol 2: aq. HI View Scheme
参考文献
Journal of the Chemical Society, , p. 1801 - 1805
反应条件
1: further solvent(s) 2: KOH View Scheme
参考文献
F: PerFHalOrg.9, 7, page 50 - 101
