4-硝基-1H-吡唑-3-羧酰胺合成路线 （共 3 条）
反应条件
pyridine; bis(trichloromethyl) carbonate in dichloromethane T=20°C; 16 h; Inert atmosphere;
参考文献
Semeraro, Teresa; Mugnaini, Claudia; Manetti, Fabrizio; Pasquini, Serena; Corelli, Federico
Tetrahedron, 2008 , vol. 64, # 49 p. 11249 - 11255
反应条件
palladium-on-charcoal in methanol T=20°C; P=1034.32 Torr; 2 h;
参考文献
HERCULES TECHNOLOGY MANAGEMENT CO V, INC.; BLAGG, Julian
Patent: WO2011/35009 A1, 2011 ;
Location in patent: Page/Page column 79-80 ;
反应条件
sodium hydroxide; bromine in water 1.) 0 deg C, 1 h, 2.) 50-55 deg C1.5 h;
参考文献
Shevelev, S. A.; Vinogradov, V. M.; Dalinger, I. L.; Cherkasova, T. I.
Russian Chemical Bulletin, 1993 , vol. 42, # 11 p. 1861 - 1864
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 11 p. 1945 - 1948
