N-(2-(溴甲基)-5-硝基苯基)乙酰胺合成路线 （共 5 条）
反应条件
1: 42.2 percent / CaCO3 / dioxane; H2O / 3 h / Heating 2: 100 percent / hydrochloric acid / 16 h / 20 °C View Scheme
参考文献
Hu, Longqin; Yu, Chengzhi; Jiang, Yongying; Han, Jiye; Li, Zhuorong; Browne, Patrick; Race, Paul R.; Knox, Richard J.; Searle, Peter F.; Hyde, Eva I.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 23 p. 4818 - 4821
反应条件
N-bromosuccinmide in tetrachloromethane
20 h; Photolysis;
参考文献
Hu, Longqin
Patent: US2004/214798 A1, 2004 ;
Location in patent: Page 11 ;
反应条件
1: 84 percent / pyridine / CHCl3 / 6 h / 20 °C
2: 55.6 percent Turnov. / N-bromosuccinimide / CCl4 / 20 h / 20 °C / Photolysis
View Scheme
参考文献
Li, Zhuorong; Han, Jiye; Jiang, Yongying; Browne, Patrick; Knox, Richard J.; Hu, Longqin
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4171 - 4178
反应条件
1: 73.3 percent Turnov. / 18-crown-6 / tetrahydrofuran / 24 h / 20 °C
2: 63.8 percent / hydrochloric acid / 5 h / 50 °C
View Scheme
参考文献
Li, Zhuorong; Han, Jiye; Jiang, Yongying; Browne, Patrick; Knox, Richard J.; Hu, Longqin
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4171 - 4178
反应条件
calcium carbonate in 1,4-dioxane; water
3 h; Heating;
参考文献
Hu, Longqin
Patent: US2004/214798 A1, 2004 ;
Location in patent: Page 11 ;
