1-(2-溴乙基)-4-氟苯合成路线

52780-14-01-(3-溴苯基)乙醇→65130-46-31-(2-溴乙基)-4-氟苯

参考文献

ABBOTT LABORATORIES
Patent: WO2007/76034 A2, 2007 ;
Location in patent: Page/Page column 168 ;

459-47-21-乙基-4-氟苯→65130-46-31-(2-溴乙基)-4-氟苯

参考文献

CONSTELLATION PHARMACEUTICALS; ALBRECHT, Brian, K.; AUDIA, James, Edmund; COOK, Andrew, S.; DAKIN, Les, A.; DUPLESSIS, Martin; GEHLING, Victor, S.; HARMANGE, Jean-Christophe; NAVESCHUK, Christopher, G.; VASWANI, Rishi, G.
Patent: WO2013/120104 A2, 2013 ;
Location in patent: Paragraph 00330 ;

403-41-81-(4-氟苯基)-1-乙醇→65130-46-31-(2-溴乙基)-4-氟苯

参考文献

Gruenenthal GmbH
Patent: US2012/46301 A1, 2012 ;
Location in patent: Page/Page column 30; 31 ;
US 20120046301 A1

462-06-6氟苯→65130-46-31-(2-溴乙基)-4-氟苯

参考文献

US2012/46301 A1, ;
US 20120046301 A1

403-42-94-氟苯乙酮→65130-46-31-(2-溴乙基)-4-氟苯

参考文献

US2012/46301 A1, ;
US 20120046301 A1

75-89-82,2,2-三氟乙醇+65130-46-31-(2-溴乙基)-4-氟苯→403-41-81-(4-氟苯基)-1-乙醇+823189-13-5

参考文献

Richard, John P.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1383 - 1396

75-89-82,2,2-三氟乙醇+64-19-7醋酸+65130-46-31-(2-溴乙基)-4-氟苯→403-41-81-(4-氟苯基)-1-乙醇+2928-12-3

参考文献

Richard, John P.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1383 - 1396

67-56-1甲醇+75-89-82,2,2-三氟乙醇+65130-46-31-(2-溴乙基)-4-氟苯→403-41-81-(4-氟苯基)-1-乙醇

参考文献

Richard, John P.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1383 - 1396

65130-46-31-(2-溴乙基)-4-氟苯→403-42-94-氟苯乙酮

参考文献

Hu, Yu Lin; Liu, Qi Fa; Lu, Ting Ting; Lu, Ming
Catalysis Communications, 2010 , vol. 11, # 10 p. 923 - 927

75-89-82,2,2-三氟乙醇+65130-46-31-(2-溴乙基)-4-氟苯→403-41-81-(4-氟苯基)-1-乙醇+823189-13-5

参考文献

Richard, John P.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1383 - 1396