10,11-二氢-N-(甲基-D3)-5H-二苯并[b,f]氮杂卓-5-丙胺合成路线 (共 3 条)
反应条件
sodium carbonate in methanol; water T=0 - 110°C; Inert atmosphere;
参考文献
Hanson, Kelsey L.; VandenBrink, Brooke M.; Babu, Kantipudi N.; Allen, Kyle E.; Nelson, Wendel L.; Kunze, Kent L.
Drug Metabolism and Disposition, 2010 , vol. 38, # 6 p. 963 - 972
反应条件
liver microsomes of a rat other reagent (anodic oxidation); Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 104, # 9 p. 2639 - 2641
反应条件
1: T=37°C; 0.05 h; aq. phosphate bufferEnzymatic reaction;
2: With NADPH
aq. phosphate buffer;
参考文献
Hanson, Kelsey L.; VandenBrink, Brooke M.; Babu, Kantipudi N.; Allen, Kyle E.; Nelson, Wendel L.; Kunze, Kent L.
Drug Metabolism and Disposition, 2010 , vol. 38, # 6 p. 963 - 972