乙基1,2,4-三嗪-3-羧酸酯合成路线 （共 4 条）
反应条件
potassium hydroxide in ethanol T=20°C; 0.25 h;
参考文献
Palmer, Andreas Marc; Grobbel, Burkhard; Brehm, Christof; Zimmermann, Peter Jan; Buhr, Wilm; Feth, Martin Philipp; Holst, Hans Christof; Simon, Wolfgang Alexander
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 24 p. 7647 - 7660
反应条件
in ethanol
1.) room temperature, 16 h, 2.) reflux, 1 h;
参考文献
Benson, Scott C.; Gross, Jonathan L.; Snyder, John K.
Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3257 - 3269
反应条件
1: With acetic acid in tetrahydrofuran; ethanol
T=-78°C; 0.5 h;
2: With triethylamine
T=25°C; 24 h;
参考文献
Akritopoulou-Zanze, Irini; Wang, Ying; Zhao, Hongyu; Djuric, Stevan W.
Tetrahedron Letters, 2009 , vol. 50, # 42 p. 5773 - 5776
反应条件
in chloroform
T=60°C; 24 h;
参考文献
Boger,D.L.; Panek,J.S.
Journal of the American Chemical Society, 1985 , vol. 107, p. 5745
