4-氯-8-甲氧基-2-甲基喹啉合成路线 （共 8 条）
反应条件
N,N-dimethyl-aniline; trichlorophosphate 2 h; Heating;
参考文献
Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630
反应条件
1: 48.7 percent / diphenyl ether; various solvent(s) / 3 h / 235 °C 2: 81.9 percent / phosphorus oxychloride; N,N-dimethylaniline / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 7 p. 1617 - 1630
反应条件
1: 99.8 percent / AcOH / benzene / 8 h / Heating 2: 48.7 percent / diphenyl ether; various solvent(s) / 3 h / 235 °C 3: 81.9 percent / phosphorus oxychloride; N,N-dimethylaniline / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 47, # 7 p. 1617 - 1630
反应条件
1: 70.4 percent / boron tribromide / 2 h / Heating 2: 83.6 percent / dioxane / 6 h / Heating View Scheme
参考文献
Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630
反应条件
boron tribromide 2 h; Heating;
参考文献
Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630
反应条件
pyridine in ethanol
8 h; Heating;
参考文献
Sathi; Gujrati; Sharma; Nath; Bhargava; Shanker
Archiv der Pharmazie, 1983 , vol. 316, # 9 p. 767 - 772
反应条件
1: 94 percent / acetone / Heating
2: 33.5 percent / NaOH / H2O / 1.5 h / Heating
View Scheme
参考文献
Avetisyan; Aleksanyan; Ambartsumyan
Russian Journal of Organic Chemistry, 2005 , vol. 41, # 5 p. 769 - 771
反应条件
1: 70.4 percent / boron tribromide / 2 h / Heating
2: 85.5 percent / dioxane / 6 h / Heating
View Scheme
参考文献
Sawada, Yuki; Kayakiri, Hiroshi; Abe, Yoshito; Imai, Keisuke; Mizutani, Tsuyoshi; Inamura, Noriaki; Asano, Masayuki; Aramori, Ichiro; Hatori, Chie; Katayama, Akira; Oku, Teruo; Tanaka, Hirokazu
Journal of Medicinal Chemistry, 2004 , vol. 47, # 7 p. 1617 - 1630
