2,6-二氯-4-甲氧基苯胺合成路线 (共 21 条)
反应条件
hydrogenchloride in diethyl ether T=-10 - 0°C; 1 h;
参考文献
Kenny, Jane R.; Maggs, James L.; Meng, Xiaoli; Sinnott, Deborah; Clarke, Stephen E.; Park, B. Kevin; Stachulski, Andrew V.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 11 p. 2816 - 2825
反应条件
sodium dithionite in ethanol; water 14 h; Heating;
参考文献
Joshi; Vyas; Duffel; Parkin; Lehmler
Synthesis, 2011 , # 7 p. 1045 - 1054
反应条件
1: HNO3; H2SO4 / CH2Cl2 / 18 h / 20 °C 2: 7 percent / Na2S2O4 / aq. ethanol / 2 h / Heating View Scheme
参考文献
Chemical Research in Toxicology, , vol. 12, # 8 p. 690 - 699
反应条件
chlorine in 1,4-dioxane
参考文献
Journal of Organic Chemistry, , vol. 30, p. 3837 - 3840
反应条件
1: 3,5-Dichlorophenol With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 2: With aniline; sodium hydroxide in water 3: dimethyl sulfate Further stages;
参考文献
Synthesis, , # 7 p. 1045 - 1054
反应条件
1: diluted sulfuric acid; sodium nitrate 2: potassium carbonate; xylene 3: tin; concentrated hydrochloric acid View Scheme
参考文献
Journal of the Chemical Society, , p. 2218
Journal of the Chemical Society, , p. 331
反应条件
1: potassium carbonate; xylene 2: tin; concentrated hydrochloric acid View Scheme
参考文献
Journal of the Chemical Society, , p. 2218
Journal of the Chemical Society, , p. 331
反应条件
hydrogenchloride; methanol T=0°C;
参考文献
Chemische Berichte, , vol. 8, p. 897
反应条件
tin in hydrogenchloride Reduction; 1 h; Heating;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 42, # 11 p. 1075 - 1083
反应条件
1: With sulfuric acid; nitric acid in dichloromethane 18 h; 2: With sodium dithionite in ethanol; water 14 h; Heating;
参考文献
Synthesis, , # 7 p. 1045 - 1054