1.1: K2CO3 / acetone / 6 h / Heating 2.1: aq. HCl / 5 h / Heating 3.1: aq. HCl; NaNO2 / 0.5 h / 10 °C 3.2: aq. HBF4 3.3: xylene / 1 h / Heating 4.1: 3.99 g / BBr3 / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Mewshaw, Richard E.; Edsall Jr., Richard J.; Yang, Cuijian; Manas, Eric S.; Xu, Zhang B.; Henderson, Ruth A.; Keith Jr., James C.; Harris, Heather A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 12 p. 3953 - 3979
1.1: K2CO3 / acetone / 6 h / Heating
2.1: aq. HCl / 5 h / Heating
3.1: aq. HCl; NaNO2 / 0.5 h / 10 °C
3.2: aq. HBF4
3.3: xylene / 1 h / Heating
View Scheme
参考文献
Mewshaw, Richard E.; Edsall Jr., Richard J.; Yang, Cuijian; Manas, Eric S.; Xu, Zhang B.; Henderson, Ruth A.; Keith Jr., James C.; Harris, Heather A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 12 p. 3953 - 3979
1.1: K2CO3 / acetone / 6 h / Heating
2.1: aq. HCl / 5 h / Heating
3.1: aq. HCl; NaNO2 / 0.5 h / 10 °C
3.2: aq. HBF4
3.3: xylene / 1 h / Heating
4.1: 3.99 g / BBr3 / CH2Cl2 / 0 - 20 °C
5.1: 62 percent / Br2; acetic acid / 1 h / 100 °C
6.1: 41 percent / SnCl2; aq. HCl; acetic acid / 1 h / 100 °C
View Scheme
参考文献
Mewshaw, Richard E.; Edsall Jr., Richard J.; Yang, Cuijian; Manas, Eric S.; Xu, Zhang B.; Henderson, Ruth A.; Keith Jr., James C.; Harris, Heather A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 12 p. 3953 - 3979
