4-羟甲基哌啶合成路线

6457-49-44-羟甲基哌啶

1032825-19-6

参考文献

WO2011/147951 A1, ;
WO 2011/147951 A1

6457-49-44-羟甲基哌啶+

24424-99-5二碳酸二叔丁酯

123855-51-6N-Boc-4-哌啶甲醇

参考文献

CHROMA THERAPEUTICS LTD.
Patent: WO2008/40934 A1, 2008 ;
Location in patent: Page/Page column 67-68 ;
WO 2008/040934 A1

6457-49-44-羟甲基哌啶+

34619-03-9

123855-51-6N-Boc-4-哌啶甲醇

参考文献

Apodaca, Richard L.; Dvorak, Curt A.; Shah, Chandravadan R.; Xiao, Wei
Patent: US2004/87573 A1, 2004 ;
Location in patent: Page 21 ;
US 20040087573 A1

6457-49-44-羟甲基哌啶

123855-51-6N-Boc-4-哌啶甲醇

参考文献

Gilissen; Bormans; De Groot; Verbruggen
Journal of Labelled Compounds and Radiopharmaceuticals, 1999 , vol. 42, # 13 p. 1289 - 1300

6457-49-44-羟甲基哌啶+

501-53-1氯甲酸苄酯

122860-33-7N-Cbz-4-羟甲基哌啶

参考文献

INSTITUT PASTEUR KOREA; KIM, Junwon; CECHETTO, Jonathan; NO, Zaesung; CHRISTOPHE, Thierry; KIM, Taehee; NAM, Ji, Youn; SO, Wonyoung; JO, Mina; OK, Taedong; PARK, Changmin; SEO, Min, Jung; SOHN, Jeong-Hun; SOMMER, Peter; BOESE, Annette, Sophia; HAN, Sung-Jun; PARK, Young, Sam; KIM, Hwa, Pyung
Patent: WO2010/46780 A2, 2010 ;
Location in patent: Page/Page column 63-64 ;

6457-49-44-羟甲基哌啶+

1885-14-9氯甲酸苯酯

122860-33-7N-Cbz-4-羟甲基哌啶

参考文献

SmithKline Beecham plc
Patent: EP1051413 B1, 2003 ;

6457-49-44-羟甲基哌啶+

31139-36-3二碳酸二苄酯

122860-33-7N-Cbz-4-羟甲基哌啶

参考文献

Pfizer Inc.
Patent: US4968704 A1, 1990 ;

6457-49-44-羟甲基哌啶

138163-08-31-Cbz-4-哌啶甲醛

参考文献

Qi, Xian Liang; Yang, Er Qun; Zhang, Jun Tao; Wang, Tao; Cao, Xiao Ping
Chinese Chemical Letters, 2012 , vol. 23, # 6 p. 661 - 664

6457-49-44-羟甲基哌啶

145508-94-7N-Boc-4-碘甲基哌啶

参考文献

Ashford, Mark E.; Nguyen, Vu H.; Greguric, Ivan; Pham, Tien Q.; Keller, Paul A.; Katsifis, Andrew
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 5 p. 783 - 794

6457-49-44-羟甲基哌啶

340962-95-0

参考文献

Ting, Pauline C; Lee, Joe F; Anthes, John C; Shih, Neng-Yang; Piwinski, John J
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 491 - 494