3-异丙氨基-1,2-丙二醇合成路线 (共 2 条)
反应条件
sodium methylate in methanol
Industry scale; Product distribution / selectivity;
参考文献
CORDEN PHARMA IP LIMITED; O'NEILL, John, A.; SCHICKANEDER, Helmut; NIKOLOPOULOS, Aggelos; JAS, Gerhard
Patent: WO2010/61366 A1, 2010 ;
Location in patent: Page/Page column 6-7 ;
反应条件
in ethanol
3 h; Ambient temperature;
参考文献
Leclerc, Gerard; Bieth, Nicole; Schwartz, Jean
Journal of Medicinal Chemistry, 1980 , vol. 23, # 6 p. 620 - 624