1: triethylamine / dichloromethane / 2 h / 0 - 20 °C 2: trichlorophosphate / toluene / 0.75 h / |Reflux 3: sodium tetrahydroborate / methanol / 18 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Santangelo Freel, Rose M.; Ogden, Kevin K.; Strong, Katie L.; Khatri, Alpa; Chepiga, Kathryn M.; Jensen, Henrik S.; Traynelis, Stephen F.; Liotta, Dennis C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 13 p. 5351 - 5381