(7CI,8CI,9CI)-1-(三氟乙酰基)-吡咯烷合成路线 (共 5 条)
反应条件
1: 1-bromo-4-isopropylbenzene With magnesium in tetrahydrofuran Inert atmosphere; 2: 2,2,2-trifluoro-1-pyrrolidin-1-ylethanone in tetrahydrofuran Inert atmosphereReflux;
参考文献
Journal of Medicinal Chemistry, , vol. 53, # 15 p. 5667 - 5675
反应条件
hydrogen; palladium nanoparticles embedded in polysiloxane matrix
参考文献
Trapp, Oliver; Weber, Sven K.; Bauch, Sabrina; Hofstadt, Werner
Angewandte Chemie - International Edition, 2007 , vol. 46, # 38 p. 7307 - 7310
反应条件
samarium diiodide in tetrahydrofuran
Ambient temperature;
参考文献
Collin, J.; Namy, J. L.; Jones, G.; Kagan, H. B.
Tetrahedron Letters, 1992 , vol. 33, # 21 p. 2973 - 2976
反应条件
in diethyl ether
T=20°C; 0.5 h;
参考文献
Suarez, Cristina; Nicholas, Elisabeth J.; Bowman, Molly R.
Journal of Physical Chemistry A, 2003 , vol. 107, # 17 p. 3024 - 3029
反应条件
16 h; Ambient temperature;
参考文献
Laduron, Frederic; Nyns, Claire; Janousek, Zdenek; Viehe, Heinz G.
Advanced Synthesis and Catalysis, 1997 , vol. 339, # 8 p. 697 - 707