sodium tetrahydroborate in 1,4-dioxane; water T=30 - 40°C; 0.5 h;

lithium aluminium tetrahydride in diethyl ether

1: 1) HCl, NaNO2; 2) CH3COONa*3H2O, CuSO4*5H2O, Na2SO3 / 1) H2O, 0-5 deg C; 2) 2 h, 10-20 deg C; 3) aq. HCl 2: 99 percent / NaBH4 / dioxane; H2O / 0.5 h / 30 - 40 °C View Scheme

N-benzyl-N,N,N-triethylammonium chloride; water; potassium acetate 1) 4 h, 60 deg C, DMSO; 2) aq.HCl, EtOH, 7 h reflux; Yield given. Multistep reaction;

thionyl chloride in pyridine; chloroform T=10 - 20°C; 48 h;

2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; copper diacetate in water; acetonitrile T=20°C; 6 h; Green chemistry;

potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran; water T=30 - 45°C; 32 h; Inert atmosphere; Product distribution / selectivity;

1: 4-isopropyl-2-bromo-5-fluoroanisole With n-butyllithium; tri-isopropoxy-borane in tetrahydrofuran; hexane; toluene T=-80 - -10°C; 1 h; Inert atmosphere; 2: (2-chloro-5-(trifluoromethyl)phenyl)methanol With 1,1'-bis(di-tert-butylphosphino)ferrocene palladium dichloride in tetrahydrofuran; hexane; water; toluene T=20°C; Suzuki Coupling; 12 h;