1: 75 percent / BF3*Et2O / 48 h / 0 °C 2: 80 percent / Ph3P, DEAD / tetrahydrofuran / 3 h / Ambient temperature 3: 91 percent / K2CO3 / CH2Cl2; methanol / 1 h / Ambient temperature 4: 1.) MsCl, pyridine, 2.) NBu4I, BaCO3, pyridine 5: Hg(OAc)2 6: 1.) BSA, 2.) TMSTf / 1.) MeCN, reflux, 2.) room temperature, 7 h 7: 69 percent / BBr3 / CH2Cl2 / 0.25 h / -78 °C View Scheme

hydrogenchloride in 1,4-dioxane Heating;

1: hydrogenchloride / water; 1,4-dioxane / 90 °C 2: acetic anhydride; dimethyl sulfoxide / 12 h / 20 °C View Scheme