2-甲基噻唑-4-甲酸乙酯合成路线 （共 44 条）
参考文献
Zhan, Weiqiang; Jiang, Yi; Brodie, Peggy J.; Kingston, David G. I.; Liotta, Dennis C.; Snyder, James P.
Organic Letters, 2008 , vol. 10, # 8 p. 1565 - 1568
反应条件
trichloromonobromomethane; 1,5-diazabicyclolt;5.3.0gt;undecane in dichloromethane T=0°C; 6 h;
参考文献
Williams, David R.; Lowder, Patrick D.; Gu, Yu-Gui; Brooks, Dawn A.
Tetrahedron Letters, 1997 , vol. 38, # 3 p. 331 - 334
反应条件
oxygen; potassium carbonate in N,N-dimethyl-formamide T=80°C; 7 h; Molecular sieve;
参考文献
Huang, Yue; Gan, Haifeng; Li, Shang; Xu, Jinyi; Wu, Xiaoming; Yao, Hequan
Tetrahedron Letters, 2010 , vol. 51, # 13 p. 1751 - 1753
反应条件
Lawesson's reagent in 1,4-dioxane 12 h; Reflux;
参考文献
Tetrahedron Letters, , vol. 55, # 16 p. 2671 - 2674
反应条件
boron trifluoride diethyl etherate in ethylene glycol dimethyl ether 3 h; Heating;
参考文献
Kim, Hong-Seok; Kwon, Il-Cheon; Kim, Oh-Hwoan
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 3 p. 937 - 940
反应条件
1: bromine / diethyl ether / 20 - 35 °C / |Inert atmosphere 2: ethanol / 20 °C / |Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 14, # 24 p. 6354 - 6357
反应条件
1: With potassium acetate in methanol T=0°C; 4 h; 2: With manganese(IV) oxide in acetonitrile Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 9 p. 1279 - 1286
反应条件
1: Et3N / acetonitrile / 1 h / 20 - 90 °C 2: CSA / toluene / 12 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 8 p. 1203 - 1208
反应条件
1: Et3N / CH2Cl2 2: phenanthrene-9,10-dione / benzene View Scheme
参考文献
Journal of the Chemical Society. Perkin transactions 1, , vol. 12, p. 1061 - 1065
反应条件
1: sodium hydride; 18-crown-6 ether / toluene / 3 h / 20 - 60 °C / |Cooling with ice 2: Lawesson's reagent / 1,4-dioxane / 12 h / |Reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 55, # 16 p. 2671 - 2674
