2-氨基吲哚-3-羧酸乙酯合成路线 （共 11 条）
反应条件
diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate; palladium 10 on activated carbon in ethanol 10 h; RefluxInert atmosphere; chemoselective reaction;
参考文献
Xing, Ruiguang; Tian, Qiuping; Liu, Qiang; Li, Yanan
Chinese Journal of Chemistry, 2013 , vol. 31, # 2 p. 263 - 266
反应条件
diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate; palladium 10 on activated carbon in ethanol Reflux;
参考文献
Xing, Ruiguang; Tian, Qiuping; Liu, Qiang; Li, Yanan
Chinese Journal of Chemistry, 2013 , vol. 31, # 2 p. 263 - 266
反应条件
1: With potassium carbonate; L-proline in water; dimethyl sulfoxide Ullmann type coupling; 0.25 h; Inert atmosphere; 2: With copper(l) iodide in water; dimethyl sulfoxide T=60°C; Ullmann type coupling; 12 h; Inert atmosphere;
参考文献
Yang, Xiaobo; Fu, Hua; Qiao, Renzhong; Jiang, Yuyang; Zhao, Yufen
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 6 p. 1035 - 1038
反应条件
1: With potassium carbonate; L-proline in water; dimethyl sulfoxide Ullmann type coupling; 0.25 h; Inert atmosphere; 2: With copper(l) iodide in water; dimethyl sulfoxide T=60°C; Ullmann type coupling; 12 h; Inert atmosphere;
参考文献
Yang, Xiaobo; Fu, Hua; Qiao, Renzhong; Jiang, Yuyang; Zhao, Yufen
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 6 p. 1035 - 1038
反应条件
1: With copper(l) iodide; potassium carbonate in dimethyl sulfoxide T=120°C; 0.166667 h; 2: With hydrogenchloride in water; dimethyl sulfoxide T=0°C;
参考文献
Kobayashi, Kazuhiro; Komatsu, Toshihide; Yokoi, Yuki; Konishi, Hisatoshi
Synthesis, 2011 , # 5 p. 764 - 768
反应条件
1: potassium tert-butylate / tetrahydrofuran / 48 h / |Reflux 2: zinc; acetic acid / 2.5 h / 55 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 20 p. 6123 - 6133,11
反应条件
1: potassium tert-butylate / tetrahydrofuran / 48 h / |Reflux 2: zinc; acetic acid / 2.5 h / 55 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 20 p. 6123 - 6133,11
反应条件
1.1: toluene 2.1: copper(l) iodide; potassium carbonate / dimethyl sulfoxide / 0.17 h / 120 °C 2.2: 0 °C View Scheme
参考文献
Synthesis, , # 5 p. 764 - 768
反应条件
sodium hydride in tetrahydrofuran
2 h; Heating;
参考文献
Lauria, Antonino; Patella, Chiara; Diana, Patrizia; Barraja, Paola; Montalbano, Alessandra; Cirrincione, Girolamo; Dattolo, Gaetano; Almerico, Anna Maria
Heterocycles, 2003 , vol. 60, # 12 p. 2669 - 2675
参考文献
Lauria, Antonino; Patella, Chiara; Diana, Patrizia; Barraja, Paola; Montalbano, Alessandra; Cirrincione, Girolamo; Dattolo, Gaetano; Almerico, Anna Maria
Heterocycles, 2003 , vol. 60, # 12 p. 2669 - 2675
