3-乙酰基-7-甲氧基香豆素合成路线 （共 11 条）
反应条件
AlCl3, aluminium chloride in toluene 3 h; Reflux;
参考文献
Starcevic, Stefan; Brozic, Petra; Turk, Samo; Cesar, Jozko; Lanisnik Rizner, Tea; Gobec, Stanislav
Journal of Medicinal Chemistry, 2011 , vol. 54, # 1 p. 248 - 261
反应条件
piperidine in ethanol
4 h; Reflux;
参考文献
Kumar, B Vinay; Naik, Halehatty S. Bhojya; Girija; Kumar, B Vijaya
Journal of Chemical Sciences, 2011 , vol. 123, # 5 p. 615 - 621
反应条件
piperidine in diethyl ether
T=0 - 20°C; Knoevenagel Condensation; 2 h;
参考文献
Bag, Seema; Ghosh, Sanjukta; Tulsan, Rekha; Sood, Abha; Zhou, Weihong; Schifone, Christine; Foster, Michelle; Levine III, Harry; Toeroek, Bela; Toeroek, Marianna
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2614 - 2618
反应条件
piperidine in ethanol
Knoevenagel cyclization;
参考文献
Secci, Daniela; Carradori, Simone; Bolasco, Adriana; Chimenti, Paola; Yanez, Matilde; Ortuso, Francesco; Alcaro, Stefano
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 10 p. 4846 - 4852
参考文献
Verma, Sanny; Kumar, Subodh; Jain, Suman L.; Sain, Bir
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 6943 - 6948
反应条件
piperidine in methanol
T=20°C; Knoevenagel condensation;
参考文献
O'Callaghan, Conor N.; McMurry, T. Brian H.
Journal of Chemical Research, Miniprint, 1997 , # 3 p. 643 - 649
反应条件
bovine tendon hydrolysate in neat (no solvent)
T=55°C; 72 h; Green chemistry;
参考文献
Sangsuwan, Rapeepat; Sangher, Sasithorn; Aree, Thammarat; Mahidol, Chulabhorn; Ruchirawat, Somsak; Kittakoop, Prasat
RSC Advances, 2014 , vol. 4, # 26 p. 13708 - 13718
反应条件
1: ethanol / 6 h / Reflux
2: potassium carbonate / water; N,N-dimethyl-formamide / 1 h
View Scheme
参考文献
Garcia-Beltran, Olimpo; Mena, Natalia; Perez, Edwin G.; Cassels, Bruce K.; Nunez, Marco T.; Werlinger, Francisca; Zavala, Daniel; Aliaga, Margarita E.; Pavez, Paulina
Tetrahedron Letters, 2011 , vol. 52, # 49 p. 6606 - 6609
反应条件
1: trichlorophosphate / acetonitrile / 2 h / 0 - 5 °C
2: ethanol / 6 h / Reflux
3: potassium carbonate / water; N,N-dimethyl-formamide / 1 h
View Scheme
参考文献
Garcia-Beltran, Olimpo; Mena, Natalia; Perez, Edwin G.; Cassels, Bruce K.; Nunez, Marco T.; Werlinger, Francisca; Zavala, Daniel; Aliaga, Margarita E.; Pavez, Paulina
Tetrahedron Letters, 2011 , vol. 52, # 49 p. 6606 - 6609
反应条件
potassium carbonate in water; N,N-dimethyl-formamide
Williamson synthesis; 1 h;
参考文献
Garcia-Beltran, Olimpo; Mena, Natalia; Perez, Edwin G.; Cassels, Bruce K.; Nunez, Marco T.; Werlinger, Francisca; Zavala, Daniel; Aliaga, Margarita E.; Pavez, Paulina
Tetrahedron Letters, 2011 , vol. 52, # 49 p. 6606 - 6609
