xanthine oxidase 120 h; 4N NaOH, potassium phosphate buffer, pH 8.0;

1: 86 percent / acetonoxime, 2 N HCl / H2O; methanol / 2 h / 50 °C / pH 4 2: 76 percent / methanol / 120 h 3: 96 percent / NH3(g) / propan-1-ol / 36 h / Ambient temperature 4: 86 percent / Na2S2O4 / H2O / 24 h / Heating 5: 67 percent / dimethylformamide / 12 h / 160 °C 6: 45 percent / 1) 90percent aq. Na2S2O4, 0.5M NaOH, 15 min, reflux; 2) O.1M NaOH, O.1M KMnO4, r.t., 10 min 7: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme

1: 72 percent / SeO2 / H2O; dioxane / 16 h / Heating 2: 86 percent / acetonoxime, 2 N HCl / H2O; methanol / 2 h / 50 °C / pH 4 3: 76 percent / methanol / 120 h 4: 96 percent / NH3(g) / propan-1-ol / 36 h / Ambient temperature 5: 86 percent / Na2S2O4 / H2O / 24 h / Heating 6: 67 percent / dimethylformamide / 12 h / 160 °C 7: 45 percent / 1) 90percent aq. Na2S2O4, 0.5M NaOH, 15 min, reflux; 2) O.1M NaOH, O.1M KMnO4, r.t., 10 min 8: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme

1: 80 percent / acetonoxime, 2 N HCl / H2O; methanol / 2 h / 50 °C / pH 4 2: 81 percent / methanol / 120 h 3: 96 percent / NH3(g) / propan-1-ol / 36 h / Ambient temperature 4: 89 percent / Na2S2O4 / H2O / 24 h / Heating 5: 32 percent / acetic anhydride / 2 h / Heating 6: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme

1: 76 percent / methanol / 120 h 2: 96 percent / NH3(g) / propan-1-ol / 36 h / Ambient temperature 3: 86 percent / Na2S2O4 / H2O / 24 h / Heating 4: 67 percent / dimethylformamide / 12 h / 160 °C 5: 45 percent / 1) 90percent aq. Na2S2O4, 0.5M NaOH, 15 min, reflux; 2) O.1M NaOH, O.1M KMnO4, r.t., 10 min 6: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme

1: 92 percent / acetonoxime, 2 N HCl / H2O / 2 h / 50 °C / pH 4 2: 76 percent / methanol / 120 h 3: 96 percent / NH3(g) / propan-1-ol / 36 h / Ambient temperature 4: 86 percent / Na2S2O4 / H2O / 24 h / Heating 5: 67 percent / dimethylformamide / 12 h / 160 °C 6: 45 percent / 1) 90percent aq. Na2S2O4, 0.5M NaOH, 15 min, reflux; 2) O.1M NaOH, O.1M KMnO4, r.t., 10 min 7: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme

1: 81 percent / methanol / 120 h 2: 96 percent / NH3(g) / propan-1-ol / 36 h / Ambient temperature 3: 89 percent / Na2S2O4 / H2O / 24 h / Heating 4: 32 percent / acetic anhydride / 2 h / Heating 5: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme

1: 93 percent / acetonoxime, 2 N HCl / H2O / 2 h / 50 °C / pH 4 2: 81 percent / methanol / 120 h 3: 96 percent / NH3(g) / propan-1-ol / 36 h / Ambient temperature 4: 89 percent / Na2S2O4 / H2O / 24 h / Heating 5: 32 percent / acetic anhydride / 2 h / Heating 6: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme

1: 83 percent / methanol / 120 h / 35 °C 2: 89 percent / NH3(l) / 3 h / -33 °C 3: 89 percent / Na2S2O4 / H2O / 24 h / Heating 4: 32 percent / acetic anhydride / 2 h / Heating 5: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme

1: 32 percent / acetic anhydride / 2 h / Heating 2: 87 percent / xanthine oxidase (AXO) / 120 h / 4N NaOH, potassium phosphate buffer, pH 8.0 View Scheme