3-甲基苯并[b]噻吩二氧化物合成路线 （共 11 条）
反应条件
dihydrogen peroxide; acetic acid
参考文献
Ricci
Annali di Chimica (Rome, Italy), 1953 , vol. 43, p. 323,328
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Werner
Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 509,515, 516
反应条件
toluene-4-sulfonic acid in benzene
Heating;
参考文献
Cabiddu, M.Grazia; Cabiddu, Salvatore; Cadoni, Enzo; Demontis, Stefania; Fattuoni, Claudia; Melis, Stefana
Tetrahedron, 2002 , vol. 58, # 22 p. 4529 - 4533
反应条件
dihydrogen peroxide; sodium chloride; chloroperoxidase in phosphate buffer; acetone
T=20°C; pH=2.75;
参考文献
Alvarez, Ricardo G.; Hunter, Iain S.; Suckling, Colin J.; Thomas, Michael; Vitinius, Ute
Tetrahedron, 2001 , vol. 57, # 40 p. 8581 - 8587
反应条件
1.1: BuLi / diethyl ether; hexane / 0.5 h / -25 °C
1.2: 73 percent / diethyl ether; hexane / -80 - 20 °C
2.1: 76 percent / 3-chloroperbenzoic acid / CH2Cl2 / 5 - 10 °C
3.1: 68 percent / LDA / tetrahydrofuran / 10 h / -80 - 20 °C
4.1: 95 percent / p-toluenesulfonic acid / benzene / Heating
View Scheme
参考文献
Cabiddu, M.Grazia; Cabiddu, Salvatore; Cadoni, Enzo; Demontis, Stefania; Fattuoni, Claudia; Melis, Stefana
Tetrahedron, 2002 , vol. 58, # 22 p. 4529 - 4533
反应条件
1: 76 percent / 3-chloroperbenzoic acid / CH2Cl2 / 5 - 10 °C
2: 68 percent / LDA / tetrahydrofuran / 10 h / -80 - 20 °C
3: 95 percent / p-toluenesulfonic acid / benzene / Heating
View Scheme
参考文献
Cabiddu, M.Grazia; Cabiddu, Salvatore; Cadoni, Enzo; Demontis, Stefania; Fattuoni, Claudia; Melis, Stefana
Tetrahedron, 2002 , vol. 58, # 22 p. 4529 - 4533
反应条件
1: 68 percent / LDA / tetrahydrofuran / 10 h / -80 - 20 °C
2: 95 percent / p-toluenesulfonic acid / benzene / Heating
View Scheme
参考文献
Cabiddu, M.Grazia; Cabiddu, Salvatore; Cadoni, Enzo; Demontis, Stefania; Fattuoni, Claudia; Melis, Stefana
Tetrahedron, 2002 , vol. 58, # 22 p. 4529 - 4533
反应条件
1: acetic acid anhydride
2: acetic acid; aqueous hydrogen peroxide
View Scheme
参考文献
Ricci
Annali di Chimica (Rome, Italy), 1953 , vol. 43, p. 323,328
反应条件
1: zinc chloride / 180 °C
2: acetic acid; aqueous hydrogen peroxide
View Scheme
参考文献
Werner
Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 509,515, 516
反应条件
1: water
2: zinc chloride / 180 °C
3: acetic acid; aqueous hydrogen peroxide
View Scheme
参考文献
Werner
Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 509,515, 516
反应条件
1: copper oxide-chromium oxide; quinoline / 170 °C
2: acetic acid; aqueous hydrogen peroxide
View Scheme
参考文献
Ricci
Annali di Chimica (Rome, Italy), 1953 , vol. 43, p. 323,328
