N-Boc-L-正亮氨酸合成路线 (共 27 条)
反应条件
dipyridinium dichromate in N,N-dimethyl-formamide T=25°C; 6 h;
参考文献
Sasaki, N.Andre; Hashimoto, Chiyomi; Potier, Pierre
Tetrahedron Letters, 1987 , vol. 28, # 48 p. 6069 - 6072
反应条件
lithium hydroxide in tetrahydrofuran
参考文献
Tavares, Francis X.; Deaton, David N.; Miller, Aaron B.; Miller, Larry R.; Wright, Lois L.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 17 p. 3891 - 3895
反应条件
Bacillus licheniformis in water T=37°C; pH=8.0; 15 h;
参考文献
Tetrahedron Asymmetry, , vol. 17, # 13 p. 1995 - 1999
反应条件
potassium hydroxide; potassium permanganate in water; tert-butyl alcohol T=20°C; 1 h;
参考文献
Organic letters, , vol. 3, # 6 p. 897 - 899
反应条件
1: H2 / 10percent Pd/C / 4 h / 20 °C / 760 Torr 2: 1.) diethoxytriphenylphosphorane; 2.) DMAP / 1.) toluene, 20-40 degC, 24 h; 2.) MeCN 3: 50 percent / CuBr*Me2S / toluene / 4 h / -50 °C 4: trifluoroacetic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 21 p. 3761 - 3764
反应条件
in 1,4-dioxane; water
参考文献
Tani, Hiroko; Honma, Tamaki; Fujii, Yuzo; Yoneyama, Koichi; Nakajima, Hiromitsu
Phytochemistry, 2003 , vol. 62, # 7 p. 1133 - 1140
反应条件
sodium hydroxide in 1,4-dioxane T=20°C;
参考文献
Bioorganic and medicinal chemistry letters, , vol. 14, # 1 p. 275 - 278
反应条件
1: Et3N; DMAP / CH2Cl2 / 2 h / 20 °C 2: KMnO4; KOH / 2-methyl-propan-2-ol; H2O / 1 h / 20 °C View Scheme
参考文献
Organic letters, , vol. 3, # 6 p. 897 - 899
反应条件
1: 1.) diethoxytriphenylphosphorane; 2.) DMAP / 1.) toluene, 20-40 degC, 24 h; 2.) MeCN 2: 50 percent / CuBr*Me2S / toluene / 4 h / -50 °C 3: trifluoroacetic acid View Scheme
参考文献
Tetrahedron Letters, , vol. 37, # 21 p. 3761 - 3764
反应条件
1.1: pyridine / CH2Cl2 / 0 °C 1.2: toluene / 0 °C 1.3: 94 percent / 2 Torr / Heating 2.1: toluene / 85 °C 3.1: aq. LiOH / tetrahydrofuran View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 3 p. 719 - 722