17-beta-羟基-5alpha-雄甾-1-烯-3-酮乙酸盐合成路线 （共 4 条）
反应条件
1.1: LTBA / tetrahydrofuran / 3 h / |Reflux 2.1: thionyl chloride / benzene / 5 - 8 °C 2.2: 11 h / |Reflux 2.3: 0 °C View Scheme
参考文献
Varela, Carla L.; Roleira, Fernanda M. F.; Costa, Saul C. P.; Pinto, Alexandra S. C. T.; Martins, Ana I. O. S.; Carvalho, Rui A.; Teixeira, Natercia A.; Correia-Da-Silva, Georgina; Tavares-Da-Silva, Elisiario
Helvetica Chimica Acta, 2014 , vol. 97, # 1 p. 39 - 46
反应条件
1: 99.8 percent / sodium hydroxide / methanol / 2 h / 20 °C 2: 88.9 percent / chromium trioxide / acetic acid; H2O / 1 h / 25 - 30 °C View Scheme
参考文献
Zhang, Huyue; Qiu, Zhuibai
Steroids, 2006 , vol. 71, # 13-14 p. 1088 - 1090
反应条件
sodium hydroxide in methanol T=20°C; 2 h;
参考文献
Steroids, , vol. 71, # 13-14 p. 1088 - 1090
反应条件
With lithium tri-t-butoxyaluminum hydride in tetrahydrofuran Inert atmosphereReflux;
参考文献
Varela, Carla; Tavares Da Silva, Elisiario J.; Amaral, Cristina; Correia Da Silva, Georgina; Baptista, Teresa; Alcaro, Stefano; Costa, Giosue; Carvalho, Rui A.; Teixeira, Natercia A. A.; Roleira, Fernanda M. F. Journal of Medicinal Chemistry, 2012 , vol. 55, # 8 p. 3992 - 4002
