2-(4-氟苄基)噻吩合成路线

154355-76-71-[(2R)-4-[5-[(4-氟苯基)甲基]噻吩-2-基]丁-3-炔-2-基]-1-羟基脲

参考文献

Brooks; Stewart; Basha; Bhatia; Ratajczyk; Martin; Craig; Kolasa; Bouska; Lanni; Harris; Malo; Carter; Bell
Journal of Medicinal Chemistry, 1995 , vol. 38, # 24 p. 4768 - 4775

1003-09-42-溴噻吩+

15629-92-21,3-双(二苯基膦丙烷)二氯化镍+

352-11-44-氟氯苄

63877-96-32-(4-氟苄基)噻吩

参考文献

Abbott Laboratories
Patent: US5616596 A1, 1997 ;

6165-68-02-噻吩硼酸+

352-11-44-氟氯苄

63877-96-32-(4-氟苄基)噻吩

参考文献

Najera, Carmen; Gil-Molto, Juan; Karlstroem, Sofia
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1798 - 1811

579-49-74-氟苯基-2-噻吩酮

63877-96-32-(4-氟苄基)噻吩

参考文献

ASTRAZENECA AB
Patent: WO2006/75955 A1, 2006 ;
Location in patent: Page/Page column 37 ;
WO 2006/075955 A1

403-43-0对氟苯甲酰氯

63877-96-32-(4-氟苄基)噻吩

参考文献

Bayer Aktiengesellschaft
Patent: US5591869 A1, 1997 ;

1003-09-42-溴噻吩+

352-11-44-氟氯苄

63877-96-32-(4-氟苄基)噻吩

参考文献

Abbott Laboratories
Patent: US5580989 A1, 1996 ;

63877-96-32-(4-氟苄基)噻吩

参考文献

Abbott Laboratories
Patent: US5506261 A1, 1996 ;

1003-09-42-溴噻吩

63877-96-32-(4-氟苄基)噻吩

参考文献

Abbott Laboratories
Patent: US5616596 A1, 1997 ;

352-11-44-氟氯苄

63877-96-32-(4-氟苄基)噻吩

参考文献

Srogl, Jiri; Allred, Gary D.; Liebeskind, Lanny S.
Journal of the American Chemical Society, 1997 , vol. 119, # 50 p. 12376 - 12377

188290-36-0+

459-46-14-氟溴苄

63877-96-32-(4-氟苄基)噻吩

参考文献

Brooks; Stewart; Basha; Bhatia; Ratajczyk; Martin; Craig; Kolasa; Bouska; Lanni; Harris; Malo; Carter; Bell
Journal of Medicinal Chemistry, 1995 , vol. 38, # 24 p. 4768 - 4775