3-(3-叔丁基-4-羟基-5-甲基苯基)丙酸甲酯合成路线 (共 2 条)
反应条件
nitrogen in water; toluene; 1,2-bis-(2-hydroxyethoxy)-ethane
参考文献
Yoshitomi Pharmaceutical Industries, Ltd.
Patent: US5081280 A1, 1992 ;
反应条件
sodium 6-tert-butyl-2-methylphenoxide
alkylation of 6-tert-butyl-2-methylphenol with methyl acrylate in the presence of alkali metal (Na or K) phenoxide; Rate constant;
参考文献
Volod'kin, A. A.
Russian Chemical Bulletin, 1993 , vol. 42, # 3 p. 457 - 460
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 3 p. 504 - 507