3-羧基苯基吡哆胺 5-磷酸酯合成路线 （共 4 条）
反应条件
1: With [3H]-alpha-Ketoglutarate; 2-hydroxyethanethiol in phosphate buffer
T=25°C; inactivation; pH=7.4; 4 h;
2: With potassium hydroxide
T=20°C; denaturation; pH=12; 1 h;
参考文献
Fu, Mengmeng; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 8 p. 1581 - 1590
反应条件
1: KOH / methanol / 0.5 h / 20 °C
2: 2.4 g / sodium borohydride / methanol / 0.33 h / 0 - 5 °C
View Scheme
参考文献
Fu, Mengmeng; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 8 p. 1581 - 1590
反应条件
1: KOH / methanol / 0.5 h
2: NaBH4 / methanol / 0.17 h / 5 °C
View Scheme
参考文献
Iskander, MN; Andrews, PR; Winkler, DA; Brinkworth, RI; Paola, C Di; et al.
European Journal of Medicinal Chemistry, 1991 , vol. 26, # 2 p. 129 - 136
反应条件
1: KOH / methanol / 0.5 h / 20 °C
2: 2.4 g / sodium borohydride / methanol / 0.33 h / 0 - 5 °C
View Scheme
参考文献
Fu, Mengmeng; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 1999 , vol. 7, # 8 p. 1581 - 1590
